Improving first-line antiretroviral therapy in resource-limited settings
نویسندگان
چکیده
منابع مشابه
Improving first-line antiretroviral therapy in resource-limited settings.
PURPOSE OF REVIEW Access to first-line antiretroviral therapy in resource-limited settings has increased rapidly in the last 5 years. Newer medicines with greater potency and better safety profiles open the possibility for improving first-line antiretroviral therapy for developing countries. RECENT FINDINGS Several medicines offer the potential to improve the simplicity, safety and efficacy o...
متن کاملWhat Is the Optimal First Line Antiretroviral Therapy in Resource-Limited Settings?
Choosing an optimal first line antiretroviral therapy (ART) in resource-limited settings (RLS) involves a careful balancing act. On the one hand, we would want to ensure that patients receive the most efficacious therapy available. On the other hand, the most efficacious regimens may be too costly for countries afflicted by the dual burdens of very high HIV prevalence and of resource scarcity. ...
متن کاملEmergence of HIV drug resistance during first- and second-line antiretroviral therapy in resource-limited settings.
INTRODUCTION Antiretroviral therapy (ART) in resource-limited settings has expanded in the last decade, reaching >8 million individuals and reducing AIDS mortality and morbidity. Continued success of ART programs will require understanding the emergence of HIV drug resistance patterns among individuals in whom treatment has failed and managing ART from both an individual and public health persp...
متن کاملImproving antiretroviral therapy adherence in resource-limited settings at scale: a discussion of interventions and recommendations
Introduction: Successful population-level antiretroviral therapy (ART) adherence will be necessary to realize both the clinical and prevention benefits of antiretroviral scale-up and, ultimately, the end of AIDS. Although many people living with HIV are adhering well, others struggle and most are likely to experience challenges in adherence that may threaten virologic suppression at some point ...
متن کاملMean CD4 cell count changes in patients failing a first-line antiretroviral therapy in resource-limited settings
BACKGROUND Changes in CD4 cell counts are poorly documented in individuals with low or moderate-level viremia while on antiretroviral treatment (ART) in resource-limited settings. We assessed the impact of on-going HIV-RNA replication on CD4 cell count slopes in patients treated with a first-line combination ART. METHOD Naïve patients on a first-line ART regimen with at least two measures of ...
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ژورنال
عنوان ژورنال: Current Opinion in HIV and AIDS
سال: 2010
ISSN: 1746-630X
DOI: 10.1097/coh.0b013e3283339b41